The Citric Acid Cycle

Way more fun version.

First you have some condensation.  You synthesize citrate (lemonade) and drink this due to dehydration.  Your sister (sis) tries to take the lemonade away from you (I-conna-take) but luckily you avoid this peril by putting all the lemonade in the freezer.  This gives you frozen citrus or iso-(icicle) citrate.  Don't ask me why but for some reason (maybe because of the alpha), alpha-ketoglutarate sounded like a dead fish to me so here is a dinner platter with some fish on it.  Unfortunately this fish was rotten because you didn't realize your freezer wasn't shut properly and everything was spoiled.  Because this fish sucks (succinyl-CoA), you throw it out (succinate because it is sucks and it's "in" the garbage).  The garbage gets incinerated and you have fumarase flames going everywhere.  The fire sends up a red flag because it is bad (mal).  But red is not a good colour when you have oxaloacetate near.  Yikes!  Run for your life!  Lots of condensation like sweat will make you dehydradated and the whole cycle will start again.  Simple.

 

If you want to incorporate other pieces of this cycle just expand on the story.  For example H2O is obviously going to be added after fumarate because you have to get rid of the fire.  Also, always check with your own lecture notes to see what aspects of this cycle (that aren't shown above) you might need to know for your own class.  

 

Reference:

Nelson, D. & Cox, M. (2008). Lehninger Principles of Biochemistry (5th ed.) W. H. Freeman and Company.

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